Mei-Lang Kung Selected Research

Hepatocellular Carcinoma (Hepatoma)

11/2023	HDGF stimulates liver tumorigenesis by enhancing reactive oxygen species generation in mitochondria.
10/2022	Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma.
1/2022	Phytochemically Derived Zingerone Nanoparticles Inhibit Cell Proliferation, Invasion and Metastasis in Human Oral Squamous Cell Carcinoma.
1/2019	Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
6/2015	Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis.
2/2015	Enhanced reactive oxygen species overexpression by CuO nanoparticles in poorly differentiated hepatocellular carcinoma cells.
3/2014	Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN.
1/2013	Up-regulation of hepatoma-derived growth factor facilitates tumor progression in malignant melanoma [corrected].
2/2004	Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.
1/2003	Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity.

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Mei-Lang Kung Research Topics

Disease

15	Neoplasms (Cancer) 11/2023 - 01/2003
10	Hepatocellular Carcinoma (Hepatoma) 11/2023 - 01/2003
6	Carcinogenesis 11/2023 - 03/2012
4	Melanoma (Melanoma, Malignant) 10/2020 - 01/2013
3	Neoplasm Metastasis (Metastasis) 01/2022 - 08/2012
2	Liver Neoplasms (Liver Cancer) 10/2022 - 03/2014
2	Infections 01/2019 - 07/2017
1	Muscular Atrophy (Muscle Atrophy) 03/2024
1	Body Weight (Weight, Body) 03/2024
1	Non-alcoholic Fatty Liver Disease 03/2024
1	Carcinoma (Carcinomatosis) 01/2022
1	Mouth Neoplasms (Oral Cancer) 01/2022
1	Squamous Cell Carcinoma of Head and Neck 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2022
1	Stomach Neoplasms (Stomach Cancer) 09/2021
1	Anxiety Disorders (Anxiety Disorder) 09/2021
1	Inflammation (Inflammations) 08/2021
1	Hepatitis 12/2020
1	Fibrosis (Cirrhosis) 12/2020
1	Colorectal Neoplasms (Colorectal Cancer) 10/2020
1	Gastritis 01/2019
1	Lymphatic Metastasis 01/2019
1	Cross Infection (Nosocomial Infection) 07/2017
1	Mood Disorders (Mood Disorder) 01/2017
1	Amyloidosis 10/2016
1	Alzheimer Disease (Alzheimer's Disease) 10/2016
1	Pathologic Processes 03/2016
1	Liver Cirrhosis (Hepatic Cirrhosis) 06/2015
1	Experimental Liver Neoplasms 03/2014
1	Breast Neoplasms (Breast Cancer) 10/2012
1	Glioma (Gliomas) 03/2012
1	Neuroblastoma 08/2011
1	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2004

Drug/Important Bio-Agent (IBA)

9	hepatoma-derived growth factorIBA 11/2023 - 03/2012
3	Cadherins (E-Cadherin)IBA 01/2019 - 10/2012
2	Amyloid (Amyloid Fibrils)IBA 03/2024 - 10/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 02/2015
2	PhytochemicalsIBA 01/2022 - 01/2020
2	zingeroneIBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2012
2	Long Noncoding RNAIBA 09/2021 - 10/2020
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 09/2021 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 10/2020 - 03/2016
2	LigandsIBA 01/2019 - 01/2018
2	VimentinIBA 06/2013 - 10/2012
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2013 - 03/2012
2	GenisteinIBA 02/2004 - 01/2003
2	Phosphotransferases (Kinase)IBA 02/2004 - 01/2003
2	IsoflavonesIBA 02/2004 - 01/2003
1	Triglycerides (Triacylglycerol)IBA 03/2024
1	Forkhead Box Protein O1IBA 03/2024
1	superoxide dismutase 2IBA 11/2023
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2023
1	Fluorescent Dyes (Fluorescent Probes)IBA 11/2023
1	Superoxides (Superoxide)IBA 11/2023
1	Antineoplastic Agents (Antineoplastics)IBA 10/2022
1	Chemotactic FactorsIBA 10/2022
1	Messenger RNA (mRNA)IBA 10/2022
1	Metformin (Glucophage)FDA LinkGeneric 09/2021
1	Fluoxetine (Prozac)FDA LinkGeneric 09/2021
1	graphene oxideIBA 08/2021
1	Concanavalin AIBA 12/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	Sodium AzideIBA 10/2020
1	Anticarcinogenic AgentsIBA 01/2020
1	protoapigenoneIBA 01/2020
1	FlavonoidsIBA 01/2020
1	OxidesIBA 07/2017
1	SilverIBA 07/2017
1	CopperIBA 07/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 07/2017
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 06/2015
1	AntibodiesIBA 06/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 06/2015
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 06/2015
1	NucleolinIBA 06/2015
1	Celecoxib (Celebrex)FDA Link 03/2014
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 03/2014
1	Hormones (Hormone)IBA 06/2013
1	Peptides (Polypeptides)IBA 06/2013
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 06/2013
1	Proteins (Proteins, Gene)FDA Link 10/2012
1	Toll-Like Receptor 3IBA 08/2011
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2003
1	biochanin AIBA 01/2003
1	daidzeinIBA 01/2003
1	Caspase 3 (Caspase-3)IBA 01/2003

Therapy/Procedure

7	Therapeutics 01/2022 - 06/2013
3	Chemoprevention 01/2022 - 01/2019
1	Drug Therapy (Chemotherapy) 10/2020
1	Adjuvant Chemotherapy 01/2020